ionocyte
- Respirometry and cutaneous oxygen flux measurements reveal a negligible aerobic cost of ion regulation in larval zebrafish (Danio rerio)
Summary: The energetic cost of epithelial ion transport in larval zebrafish is estimated to be low based on relatively constant in vivo O2 flux across cutaneous ionocytes, despite widely varying rates of Na+ uptake.
- Cortisol is an osmoregulatory and glucose-regulating hormone in Atlantic sturgeon, a basal ray-finned fish
Summary: Cortisol increases during exposure to seawater and exogenous cortisol upregulates gill NKA, NKCC and H+-ATPase and plasma glucose in sturgeon; thus, cortisol is a key osmoregulatory and glucocorticoid hormone in chondrosteans.
- Reassessing the contribution of the Na+/H+ exchanger Nhe3b to Na+ uptake in zebrafish (Danio rerio) using CRISPR/Cas9 gene editing
Summary: CRISPR/Cas9 knockout of the Na+/H+ exchanger Nhe3b has no effect on Na+ uptake in larval zebrafish. H+-ATPase and Na+-Cl−-cotransporter are not responsible for maintaining Na+ uptake in nhe3b knockout mutants.
- claudin-10 isoform expression and cation selectivity change with salinity in salt-secreting epithelia of Fundulus heteroclitus
Summary: Claudin-10 protein isoforms, which form putative cation pores, change gene expression with salinity acclimation and alter ion selectivity of the paracellular pathway in salt-secreting epithelia of euryhaline mummichogs (Fundulus heteroclitus).
- Functional classification of gill ionocytes and spatiotemporal changes in their distribution after transfer from seawater to freshwater in Japanese seabass
Summary: Gill ionocytes in Japanese seabass originate from undifferentiated cells in the filaments and expand their distribution to the lamellae during freshwater acclimation.
- Ammonia exposure affects the mRNA and protein expression levels of certain Rhesus glycoproteins in the gills of climbing perch
Summary: Active ammonia excretion in the gills of the climbing perch, Anabas testudineus, may involve apical Rhag and basolateral Rhcg2 expressed in ammonia-inducible Na+/K+-ATPase α1c-immunoreactive ionocytes.
- Inhibition of calcium uptake during hypoxia in developing zebrafish is mediated by hypoxia-inducible factor
Summary: Larval zebrafish raised in hypoxic water exhibit reduced Ca2+ uptake through a reduction in the number of ecac-expressing ionocytes, and these effects are probably associated with the activation of HIF-1αb during hypoxia.
- Paracellular pathway remodeling enhances sodium secretion by teleost fish in hypersaline environments
Summary: In fish gills, secretion of NaCl into hypersaline environments requires restructuring of the specialized Na+-permeable paracellular pathway and an increase in conductance of the epithelium.