Force enhancement
- Differences in titin segmental elongation between passive and active stretch in skeletal muscle
Summary: Elongation of titin proximal and distal segments differs between passive and active stretch in skeletal muscle myofibrils, but not in an actin-dependent manner.
- Effects of a titin mutation on negative work during stretch–shortening cycles in skeletal muscles
Summary: Active muscles from mice with a small titin deletion exhibit large deficits in net negative work, suggesting that titin contributes to energy storage and dissipation during stretch–shortening cycles.