Table 3.

Results of the pharmacological screening

[Drug] (mol l–1)NDuration (min)Ltot saline (Tq h–1 cm–2)Ltot treatment (Tq h–1 cm–2)P-valueEffect
Neural testing
Neurotransmitters
   Adrenaline10–36101.64±0.920.55±0.380.29810
   Noradrenaline10–36101.50±0.820.73±0.200.39720
   5-HT10–37102.02±0.873.25±0.990.36970
   GABA10–37102.02±0.872.59±0.180.61010
   Carbachol*10–36101.64±0.920.58±0.160.30670
   KCl2 10–16102.31±0.974.37±2.660.49220
Hormonal testing
   PRL10–68603.74±0.90193.82±60.800.0167+
   MT10–68603.74±0.9071.86±13.460.0014+
   α-MSH10–68603.74±0.901.15±0.400.0265
  • * Cholinergic agonist. –, inhibition; 0, no effect; +, potentiation. PRL, prolactin; MT, melatonin; 5-HT, serotonin; α-MSH,α -melatonin-stimulating hormone; Ltot, total light emission; Tq h–1 cm–2, teraquanta per hour per square centimetre