Table 1.

Experimental groups of mice (photoperiod 07:00 h to 19:00 h)

Group numberTime of sacrifice (h)ConditionWheel access
116:00–17:30Typically resting; before the beginning of nightly running activityFive days; wheel access blocked from 13:00 h
202:00–03:30Immediately after the peak of nightly wheel-running activity [see fig. 1 in Girard and colleagues (Girard et al., 2001)]Five days plus
307:00–08:30Immediately after the dark phase, i.e. the normal activity period for both HR and C linesFive days plus
416:00–17:30Typically resting; before the beginning of nightly running activityNever had wheel access