Table 1.

Swimming and quiescent bouts for nematode worms

Mean (min)s.d.s.e.m.No. of bouts/wormsP-values
Swimming bout
   Wild-type14.110.290.5419/74n.a.
   unc-25(sa94ts)4.14.620.3308/24<0.001
   unc-25(e156)13.013.441.1152/20>0.05 n.s.
   unc-30(e318)8.814.130.8279/24<0.001
   0.01 mmol l–1 aldicarb3.93.890.2246/23<0.001
   0.1 mmol l–1 aldicarb4.23.980.652/20<0.001
   ace-1(g72);ace-2(p1000)8.16.790.4278/25<0.001
   dgk-1(nu62)4.13.440.1433/23<0.001
   glr-1::ICE(kyls36)5.29.380.4508/29<0.0001
   nmr-1::ICE(akls11)16.417.000.9343/65=0.99 n.s.
   Mock ablation (glr-1::GFP)13.19.591.177/12n.a.
   AVB ablated5.84.170.3206/16<0.0001*
   glr-1::GLR-1(A/T)10.17.930.6152/30<0.0001
   nmr-1::GLR-1(A/T)12.711.890.5470/67<0.0001
   egl-4(ks60)9.011.370.9141/24<0.001
   egl-4(ks61)4.93.340.2196/24<0.001
   egl-4(ks62)9.911.980.7292/46<0.001
   egl-4(n477)8.69.190.8144/22<0.001
Quiescent bout
   Wild-type4.82.170.1489/74n.a.
   unc-25(sa94ts)9.611.710.7309/24<0.001
   unc-25(e156)8.57.580.6159/20<0.001
   unc-30(e318)8.69.090.5292/24<0.001
   0.01 mmol l–1 aldicarb10.412.590.8250/23<0.001
   0.1 mmol l–1 aldicarb29.342.184.974/20<0.001
   ace-1(g72);ace2(–1000)10.213.070.8287/25<0.001
   dgk-1(nu62)7.26.710.3436/23<0.001
   glr-1::ICE(kyls36)7.314.640.7491/29<0.0001
   nmr-1::ICE(akls11)5.66.890.4349/65=0.1 n.s.
   Mock ablation (glr-1::GFP)7.33.020.386/12n.a.
   AVB ablated9.210.290.7213/16>0.05 n.s.*
   glr-1::GLR-1(A/T)25.929.842.4158/30<0.0001
   nmr-1::GLR-1(A/T)7.47.920.3520/67=0.0006
   egl-4(ks60)2.72.490.2173/24<0.001
   egl-4(ks61)2.20.960.1216/24<0.001
   egl-4(ks62)2.93.280.2330/46<0.001
   egl-4(n477)2.82.010.2162/22<0.001
  • P-values are for comparison with wild-type or mock ablation (*)

    n.s., non-significant difference; n.a., not applicable