Table 1.

Effect of hibernation on indices of transcription and cell cycle regulation in skeletal muscle of thirteen-lined ground squirrels

Ratio hibernating:euthermic value
Histone deacetylase
    Activity1.82±0.20
    HDAC1 protein1.21±0.05
    HDAC4 protein1.48±0.09
Histone 3
    Total H3 protein0.99±0.16
    Phospho-H30.61±0.09
    Acetyl-H30.75±0.04
RNA polymerase II
    Activity0.57±0.04
    Total Pol II protein1.05±0.19
    Phospho-Pol II1.79±0.21
  • Values are means ± s.e.m.; N=3-4 independent determinations on preparations from different individuals. Hibernating and euthermic values are significantly different (P<0.05).

    Data are modified from Morin and Storey (Morin and Storey, 2006).