Table 4.

Summary of differences in enzyme specific activities in tissues of Fundulus grandis held under normal and reduced oxygen levels for 4 weeks at 27°C

Pathway
GlycolysisGlycogen metabolismGluconeogenesis
Tissue
Muscle↓ PGI, ALD, PYK, LDH↓ GPase (Total)n.d.
Liver↑ PFK, GAPDH, PGK, LDHnone↑ MDH, FBPase
Heart↑ HKn.d.n.d.
Brain↑ HKn.d.n.d.
  • PGI, phosphoglucoisomerase; ALD, aldolase; PYK, pyruvate kinase; LDH, lactate dehydrogenase; PFK, phosphofructokinase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; PGK, phosphoglycerokinase; MDH, malate dehydrogenase; FBPase, fructose-1,6-bisphosphatase; HK, hexokinase.

    The enzymes shown are those that were significantly different between treatment groups at P≤0.001. n.d. not determined.

    ↑ Higher in hypoxia than in normoxia; ↓ Lower in hypoxia than in normoxia.