Table 1.

Amino acid sequence identity between acetylcholine receptor subunits from different species

T. californica Human
SpeciesSubunitαβγδαβγ*ϵ*δ
T. marmorata α 99 393233 78 34312733
β39 96 373438 54 393538
γ3235 97 463238 54 53 47
δ323446 98 32354239 57
H. monopterigium α 98 393233 79 34302733
β38 88 383638 54 403539
γ3038 94 463239 53 53 46
δ323445 95 32354339 58
N. tasmaniensis α 96 393232 78 34302733
δ323446 98 32354239 57
  • Values represent the percentage identity at the amino acid sequence level between the acetylcholine receptor subunits from T. marmorata, H. monopterigium and N. tasmaniensis, compared with the equivalent proteins from T. californica and humans.

  • * The acetylcholine receptor γ and ϵ subunits, present at the fetal and adult human neuromuscular junction, respectively, are equally homologous to the γ subunit in electric fish, representing a hybrid of the two.