Young mice (<485 days) | Old mice (>485 days) | ||||
---|---|---|---|---|---|
Variable | Fat and lean (absolute values) | Fat and lean (fractions of body mass) | Fat and lean (absolute values) | Fat and lean (fractions of body mass) | |
V̇ _{O2max} | Fat | r=0.509, P=0.013 | r=0.237, P=0.289 | r=0.481, P=0.0096 | r=0.152, P=0.449 |
Lean | r=0.397, P=0.060 | r=0.174, P=0.439 | r=0.346, P=0.0708 | r=0.231, P=0.245 | |
Age | r=0.207, P=0.344 | r=0.055, P=0.808 | r=0.264, P=0.174 | r=0.425, P=0.027 | |
V̇ _{O2sum} | Fat | r=0.360, P=0.091 | r=0.155, P=0.491 | r=0.121, P=0.582 | r=-0.225, P=0.259 |
Lean | r=0.466, P=0.025 | r=0.132, P=0.557 | r=0.065, P=0.767 | r=-0.289, P=0.143 | |
Age | r=0.113, P=0.608 | r=0.003, P=0.989 | r=-0.370, P=0.083 | r=-0.399, P=0.039 |
V̇_{O2max}, maximal oxygen consumption in exercise; V̇_{O2sum}, maximal oxygen consumption in thermogenesis.
Regressions were performed on animals younger and older than the `breakpoint' age of 485 days determined from the complete data set. Regression coefficients (r) and P values for fat and lean tissue content were computed from absolute tissue mass and as fractions of whole body mass; in the latter case, regressions also included whole body mass (r and P values not shown). No P value is significant after Bonferroni correction (adjusted α=0.0023 for young and old mice).