Table 1.

Potential antisporozoite effector mechanisms*

Effector strategy (target)MoleculeTarget parasiteReferences
Parasite ligandsN2 scFv Plasmodium gallinaceum Capurro et al., 2000
Tissue recognition (receptors)Lectins, mAbs Plasmodium gallinaceum Barreau et al., 1995
SM1 peptide Plasmodium berghei Ito et al., 2002
Immune response effectorsDefensins Plasmodium gallinaceum Shahabuddin et al., 1998
  • * Adapted from Nirmala and James (2003).