RT Journal Article SR Electronic T1 The effect of acute temperature increases on the cardiorespiratory performance of resting and swimming sockeye salmon (Oncorhynchus nerka) JF Journal of Experimental Biology JO J. Exp. Biol. FD The Company of Biologists Ltd SP 3915 OP 3926 DO 10.1242/jeb.019281 VO 211 IS 24 A1 Steinhausen, M. F. A1 Sandblom, E. A1 Eliason, E. J. A1 Verhille, C. A1 Farrell, A. P. YR 2008 UL http://jeb.biologists.org/content/211/24/3915.abstract AB The mechanism underlying the decrease in aerobic scope in fish at warm temperatures is not fully understood and is the focus of this research. Our study examined oxygen uptake and delivery in resting, swimming and recovering sockeye salmon while water temperature was acutely increased from 15°C to 24°C in 2°C h–1 increments. Fish swam at a constant speed during the temperature change. By simultaneously measuring oxygen consumption (ṀO2), cardiac output (Q̇) and the blood oxygen status of arterial and venous blood, we were able to determine where in the oxygen cascade a limitation appeared when fish stopped sustained swimming as temperature increased. High temperature fatigue of swimming sockeye salmon was not a result of a failure of either oxygen delivery to the gills or oxygen diffusion at the gills because oxygen partial pressure (PO2) and oxygen content (CO2) in arterial blood did not decrease with increasing temperature, as would be predicted for such limitations. Instead, arterial oxygen delivery (TaO2) was initially hampered due to a failure to adequately increase Q̇ with increasing temperature. Subsequently, lactate appeared in the blood and venous PO2 remained constant.