Genome editing for comparative physiology

Guest editors: Michael H. Dickinson, Leslie B. Vosshall and Julian A. T. Dow

For almost 100 years, biologists have made fundamental discoveries using a handful of model organisms that are not representative of the rich diversity found in nature. The advent of CRISPR genome editing now opens up a wide range of new organisms to mechanistic investigation,  increasing not only the taxonomic breadth of current research but also the scope of biological problems amenable to study. This special issue addresses a broad spectrum of biological problems in non-model organisms and highlights the utility of genome editing across levels of complexity from development and physiology to behaviour and evolution.

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