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Cover: Unlike most vertebrates, the red-eared slider Trachemys scripta is an extremely anoxia-tolerant vertebrate that can survive hours and days of anoxia at warm and cold acclimation temperatures, respectively. During anoxia at both temperatures, systemic cardiac output is substantially reduced about three- to fivefold (line graphs), reflecting a reduction in metabolic rate. At the same time, the distribution of systemic blood flow changes, increasing to tissues that are critical for anoxic survival at the expense of subsidiary tissues (pie charts). For details on the changes in blood flow distribution and absolute tissue blood flows in anoxic turtles, as well as the modulatory role of {alpha}-adrenergic vasoactivity in these changes, see the paper by J. A. W. Stecyk, J. Overgaard, A. P. Farrell and T. Wang (pp. 269-283).

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© The Company of Biologists Ltd 2005