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About the Cover
Cover:
Photomicrograph, taken with UV epi-illumination, of sensory (Xs) and motor (Xm) projections of the vagus nerve into the medulla of the sculpin, Myoxocephalus scorpius, labelled with the fluorescent neural tract tracer Fast Blue. Microinjection of glutamate into precise locations in the dorsal sensory area elicited specific cardiovascular and ventilatory responses, as illustrated in the inset figure and described in the article by Sundin, Turesson and Taylor (pp. 867-876). The cardiac response was blocked by prior injection of an antagonist to the ionotropic glutamate receptor NMDA. These data show striking similarities with work in the mammalian brainstem and represent a useful advance in our knowledge of the mechanisms of central control of the cardiorespiratory system of fish, which builds on the seminal work of Coen Ballintijn.
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