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About the Cover
Cover: The photoreceptors of Drosophila melanogaster are an important genetic model for phototransduction and G-protein-coupled signalling (see review by Hardie, pp. 3403-3409); the cover shows an in vivo confocal image of ommatidia dissociated from its compound eye. The phototransducing membrane (rhabdomere) of the constituent photoreceptors have been fluorescently labelled with a genetically targeted enhanced green fluorescent protein (EGFP)-tagged membrane protein. The rhabdomeres, which are composed of microvilli, form optical waveguides (1.5 
m x 100 m) along the length of each photoreceptor. Above and below: a cross-sectional view of the rhabdomere fluorescence in the intact eye obtained using an immersion objective. Photographs by Roger Hardie and Jeremy Skepper (Cambridge University Department of Anatomy).
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