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Appelkvist, E. L., \201berg, F., Guan, Z., Parmryd, I. and Dallner, G (1994). Regulation of coenzyme Q biosynthesis. Molec. Aspects Med 15, 37-.

Arnheim, N. and Cortopassi, G (1992). Deleterious mitochondrial DNA mutations accumulate in aging human tissues. Mutat. Res 275, 157-.[Medline]

Arroyo, A., Navarro, F., Navas, P. and Villalba, J. M (1998). Ubiquinol regeneration by plasma membrane ubiquinone reductase. Protoplasma 205, 107-.

Balcavage, W. X (1982). Reactions of malonaldehyde with mitochondrial membranes. Mech.Ageing Dev 19, 159-.[Medline]

Battino, M., Gorini, A., Villa, R. F., Genova, M. L., Bovina, C., Sassi, S., Littarru, G. P. and Lenaz, G (1995). Coenzyme Q content in synaptic and non-synaptic mitochondria from different brain regions in the ageing rat. Mech. Ageing Dev 78, 173-.[Medline]

Beyer, R. E (1994). The role of ascorbate in antioxidant protection of biomembranes: interaction with vitamin E and coenzyme Q. J. Bioenerg. Biomembr 26, 349-.[Medline]

Beyer, R. E., Burnett, B. A., Cartwright, K. J., Edington, D. W., Falzon, M. J., Kreitman, K. R., Kuhn, T. W., Ramp, B. J., Rhee, S. Y. S., Rosenwasser, M. J., Stein, M. and An, L. C (1985). Tissue Coenzyme Q (ubiquinone) and protein concentrations over the life span of the laboratory rat. Mech. Ageing Dev 32, 267-.[Medline]

Beyer, R. E., Segura-Aguilar, J., Di Bernardo, S., Cavazzoni, M., Fato, R., Fiorentini, D., Galli, M. C., Setti, M., Landi, L. and Lenaz, G (1996). The role of DT-diaphorase in the maintenance of the reduced antioxidant form of Coenzyme Q in membrane systems. Proc. Natl. Acad. Sci. USA 93, 2528-.[Abstract/Free Full Text]

Beyer, R. E., Segura-Aguilar, J., Di Bernardo, S., Cavazzoni, M., Fato, R., Fiorentini, D., Galli, M. C., Setti, M., Landi, L. and Lenaz, G (1997). The two-electron quinone reductase DT-diaphorase generates and maintains the antioxidant (reduced) form of Coenzyme Q in membranes. Molec. Aspects Med 18, 15-.

Boffoli, D., Scacco, S. C., Vergar, R., Solarino, G., Santacroce, G. and Papa, S (1996). Decline with age of the respiratory chain activity in human skeletal muscle. Biochim. Biophys.Acta 1226, 73-.

Boveris, A., Oshino, N. and Chance, B (1972). The cellular production of hydrogen peroxide. Biochem. J 128, 617-.[Medline]

Brightman, A. O., Wang, J., Miu, R. K., Sun, I. L., Barr, R., Crane, F. L. and Morre, D. J (1992). A growth factor-and hormone-stimulated NADH oxidase from rat liver plasma membrane. Biochim. Biophys. Acta 1105, 109-.[Medline]

Bruno, M., Brightman, A. O., Lawrence, J., Werderitsh, D., Morre, D. M. and Morre, D. J (1992). Stimulation of NADH Surface oxidase and oxidative stress propagation during aging 1519Table 5. Reduction of cytochrome c as a measure of superoxide production by buffy coats from the blood of agedindividuals and inhibition by coenzyme Q Rate of reduction of cytochrome c (nmolmin1106cells 1)Group N No addition+0.1mmoll1Q1035\32065 years5NDND 80\32089 years60.05\2610.02 0.03\2610.02 90\32094 years60.36\2610.070.07\2610.07 Values are means \261S.D.; ND, not detected.Q10, ubiquinone-10 (CoQ10). oxidase activity by growth factors and hormones is decreased or absent with hepatoma plasma membrane. Biochem. J 284, 625-.

Butler, J., Koppenol, W. H. and Margoliash, E (1982). Kinetics and mechanism of the reduction of ferricytochrome c by the superoxide anion. J. Biol. Chem 257, 10747-.[Abstract/Free Full Text]

Chueh, P.-J., Morre, D. M., Penel, C., DeHahn, T. and Morre, D. M (1997). The hormone-responsive NADH oxidase of the plant plasma membrane has properties of a NADH:protein disulfide reductase. J. Biol. Chem 272, 11221-.[Abstract/Free Full Text]

Dai, S., Morre, D. J., Geilen, C. C., Almond-Roesler, B., Orfanos, C. E. and Morre, D. M (1997). Inhibition of plasma membrane NADH oxidase activity and growth of HeLa cells by natural and synthetic retinoids. Mol. Cell Biochem 166, 101-.[Medline]

de Grey, A. D. N. J (1997). A proposed refinement of the mitochondrial free radical theory of aging. BioEssays 19, 161-.[Medline]

DeHahn, T., Barr, R. and Morre, D. J (1997). NADH oxidase activity present on both the external and internal surfaces of soybean plasma membranes. Biochim. Biophys. Acta 1328, 99-.

Ernster, L. and Dallner, G (1995). Biochemical, physiological and medical aspects of ubiquinone function. Biochim. Biophys. Acta 127, 195-.

Ernster, L., Forsmark, P. and Nordenbrand, K (1992). The mode of action of lipid-soluble antioxidants in biological membranes: relationship between the effects of ubiquinol and vitamin E as inhibitors of lipid peroxidation in submitochondrial particles. BioFactors 3, 241-.[Medline]

Genova, M. L., Castelluccio, C., Fato, R., Parenti Castelli, G., Merlo Pich, M., Formiggini, G., Bovina, C., Marchetti, M. and Lenaz, G (1995). Major changes in Complex I activity in mitochondria from aged rats may not be detected by direct assay of NADH\320coenzyme Q reductase. Biochem. J 311, 105-.

Harman, D (1956). Aging: a theory based on free radical and radiation chemistry. J.Gerontol 11, 298-.[Medline]

Harman, D (1972). The biologic clock: the mitochondria?. J. Am. Geriatr. Soc 20, 145-.[Medline]

Hershko, C (1992). Iron chelators in medicine. Molec. Aspects Med 13, 113-.[Medline]

Kagan, V., Serbinova, E. and Packer, L (1990). Antioxidant effects of ubiquinones in microsomes and mitochondria are mediated by tocopherol recycling. Biochem. Biophys. Res. Commun 169, 851-.[Medline]

Kalen, A., Norling, B., Appelkvist, E. L. and Dallner, G (1987). Ubiquinone biosynthesis by the microsomal fraction from rat liver. Biochim. Biophys. Acta 926, 70-.[Medline]

Kalen, A., S\232derberg, M., Elmberger, P. G. and Dallner, G (1990). Uptake and metabolism of dolichol and cholesterol in perfused rat liver. Lipids 25, 93-.[Medline]

Kennedy, A. J. and Lyons, T. J (1998). Glycation, oxidation and lipoxidation in the development of diabetic complications. Metabolism 46, 14-.

Kishi, T., Morre, D. M. and Morre, D. J (1999). The plasma membrane NADH oxidase of HeLa cells has hydroquinone oxidase activity. Biochim. Biophys. Acta 1412, 66-.[Medline]

Larm, J. A., Vaillant, F., Linnane, A. W. and Lawen, A (1994). Up-regulation of the plasma membrane oxidoreductase as a prerequisite for the viability of human Namalwa0cells. J.Biol. Chem 269, 30097-.[Abstract/Free Full Text]

Lawen, A., Martinus, R. D., McMullen, G. L., Nagley, P., Vaillant, F., Wolvetang, E. J. and Linnane, A. W (1994). The universality of bioenergetic disease: the role of mitochondrial mutation and the putative inter-relationship between mitochondria and plasma membrane NADH oxidoreductase. Mol. Aspects Med 15, 13-.

Lenaz, G (1998). Role of mitochondria in oxidative stress and aging. Biochim. Biophys. Acta 1366, 53-.[Medline]

Lenaz, G., Bovina, C., Castelluccio, C., Fato, R., Formiggini, G., Genova, M. L., Marchetti, M., MerloPich, M., Pallotti, F., Parenti Castelli, G. and Biagini, G (1997). Mitochondrial complex I defects in aging. Mol. Cell. Biochem 174, 329-.[Medline]

Lenaz, G., Cavazzoni, M., Genova, M. L., D'Aurelio, M., Merlo Pich, M., Pallotti, F., Formiggini, G., Marchetti, M., Parenti Castelli, G. and Bovina, C (1998). Oxidative stress, antioxidant defences and aging. BioFactors 8, 195-.[Medline]

Mandel, R., Ryser, H. J.-P., Ghani, F., Wu, M. and Peak, D (1993). Inhibition of a reductive function of the plasma membrane by bacitracin and antibodies against protein disulfide-isomerase. Proc. Natl. Acad. Sci. USA 90, 4112-.[Abstract/Free Full Text]

Mayo, L. A. and Curnutte, J (1990). Kinetic microplate assay for superoxide production by neutrophils and other phagocytic cells. Met. Enzymol 186, 567-.[Medline]

McCord, J. M. and Fridovich, I (1968). The reduction of cytochrome c by milk xanthine oxidase. J. Biol. Chem 243, 5753-.[Abstract/Free Full Text]

Miquel, J (1992). An update on the mitochondrial-DNA mutation hypothesis of cell aging. Mutat. Res 275, 209-.[Medline]

Miquel, J., Economos, A. C., Fleming, J. and Johnson, J. E., Jr (1980). Mitochondrial role in cell aging. Exp. Gerontol 15, 575-.[Medline]

Morre, D. J (1994). The hormone-and growth factor-stimulated NADH oxidase. J. Bioenerg. Biomembr 26, 421-.[Medline]

Morre, D. J (1995). NADH oxidase activity of HeLa plasma membranes inhibited by the antitumor sulfonylurea N -(4-methylphenylsulfonyl)- N -(4-chlorophenyl)urea (LY181984) at an external site. Biochim. Biophys. Acta 1240, 201-.[Medline]

Morre, D. J. and Brightman, A. O (1991). NADH oxidase of plasma membranes. J. Bioenerg. Biomembr 23, 469-.[Medline]

Morre, D. J., Caldwell, S., Mayorga, A., Wu, L.-Y. and Morre, D. M (1997). NADH oxidase from sera of cancer patients is inhibited by capsaicin. Arch. Biochem. Biophys 342, 224-.[Medline]

Morre, D. J., Chueh, P.-J., Lawler, J. and Morre, D. M (1998). The sulfonylurea-inhibited NADH oxidase activity of HeLa cell plasma membranes has properties of a protein disulfide\320thiol oxido-reductase with protein disulfide\320thiol interchange activity. J. Bioenerg. Biomembr 30, 477-.[Medline]

Morre, D. J., Chueh, P.-J. and Morre, D. M (1995). Capsaicin inhibits preferentially the NADH oxidase and growth of transformed cells in culture. Proc. Natl. Acad. Sci. USA 92, 1831-.[Abstract/Free Full Text]

Morre, D. J., Jacobs, E., Sweeting, M., de Cabo, R. and Morre, D. M (1997). A protein thiol\320disulfide interchange activity of HeLa plasma membranes inhibited by the antitumor sulfonylurea N -(4-methylphenylsulfonyl)- N -(4-chlorophenyl)urea (LY181984). Biochim.Biophys. Acta 1325, 117-.[Medline]

Morre, D. J. and Morre, D. M (1994). Differential response of the NADH oxidase of plasma membranes of rat liver and hepatoma and HeLa cells to thiol reagents. J. Bioenerg.Biomembr 27, 137-.

Morre, D. J. and Morre, D. M (1995). Mechanism of killing ofHeLa cells by the antitumor sulfonylurea N -(4-methylphenylsulfonyl)- N -(4-chlorophenyl)urea (LY181984). Protoplasma 184, 188-.

Morre, D. J., Pogue, R. and Morre, D. M (1999). A multifunctional ubiquinol oxidase of the external cell surface and sera. BioFactors 9, 179-.[Medline]

Morre, D. J., Sun, E., Geilen, C., Wu, L.-Y., de Cabo, R., Krasagakis, K., Orfanos, C. E. and Morre, D. M (1996). Capsaicin inhibits plasma membrane NADH oxidase and growth of human and mouse melanoma lines. Eur. J. Cancer 32, 1995-.

Morre, D. J., Wilkinson, F. E., Kim, C., Cho, N., Lawrence, J., Morre, D. M. and McClure, D (1996). Antitumor sulfonylurea-inhibited NADH oxidase of cultured HeLa plasma membranes. Biochim. Biophys. Acta 1280, 197-.[Medline]

Morre, D. J., Wu, L.-Y. and Morre, D. M (1995). The antitumor sulfonylurea N -(4-methylphenylsulfonyl)- N -(4-cholrophenyl)urea (LY181984) inhibits NADH oxidase activity of HeLa plasma membranes. Biochim. Biophys. Acta 1240, 11-.[Medline]

Navarro, F., Villalba, J. M., Crane, F. L., MacKellar, W. C. and Navas, P (1995). A phospholipid-dependent NADH\320Coenzyme Q reductase from liver plasma membrane. Biochem. Biophys. Res. Commun 212, 138-.[Medline]

Nohl, H., Gille, L., Sch\232nheit, K. and Liu, Y (1996). Conditions allowing redox-cycling ubisemiquinone in mitochondria to establish a direct redox couple with molecular oxygen. Free Rad. Biol. Med 20, 207-.[Medline]

Ozawa, T (1995). Mechanism of somatic mitochondrial DNA mutations associated with age diseases. Biochim. Biophys. Acta 1271, 177-.[Medline]

Ozawa, T (1997). Genetic and functional changes in mitochondria associated with aging. Physiol. Rev 77, 425-.[Abstract/Free Full Text]

Papa, S. and Skulachev, V. P (1997). Reactive oxygen species, mitochondria, apoptosis and aging. Mol. Cell. Biochem 174, 305-.[Medline]

Richter, C., Park, J. W. and Ames, B. N (1988). Normal oxidative damage to mitochondrial and nuclear-DNA is extensive. Proc. Natl. Acad. Sci. USA 85, 6465-.[Abstract/Free Full Text]

Shigenaga, M. K., Hagen, T. M. and Ames, B. N (1994). Oxidative damage and mitochondrial decay in aging. Proc. Natl. Acad. Sci. USA 91, 10771-.[Abstract/Free Full Text]

S\232derberg, M., Edlund, C., Kristensson, K. and Dallner, G (1990). Lipid compositions of different regions of the human brain during aging. J. Neurochem 54, 415-.[Medline]

Steinberg, D (1997). Low density lipoprotein oxidation and its pathobiological significance. J. Biol. Chem 272, 20963-.[Free Full Text]

Sun, I. L., Navas, P., Crane, F. L., Morre, D. J. and L\232w, H (1987). NADH diferric transferrin reductase activity in liver plasma membrane. J. Biol. Chem 262, 15915-.[Abstract/Free Full Text]

Takahashi, T., Okamoto, T. and Kishi, T (1996). Characterization of NADPH-dependent ubiquinone reductase activity in rat liver cytosol: effect of various factors on ubiquinone-reducing activity and discrimination from other quinone reductases. J. Biochem 119, 256-.

Takahashi, T., Yamaguchi, T., Shitashige, M., Okamoto, T. and Kishi, T (1995). Reduction of ubiquinone in membrane lipids by rat liver cytosol and its involvement in the cellular defense system against lipid peroxidation. Biochem. J 309, 883-.

Thomas, S. R., Neuzil, J. and Stocker, R (1997). Inhibition of LDL oxidation by ubiquinol-10. A protective mechanism for Coenzyme Q in atherogenesis?. Molec. Aspects Med 18, 85-.

Vaillant, F., Larm, J. A., McMullen, G. L., Wolvetang, E. J. and Lawen, A (1996). Effectors of mammalian plasma membrane NADH-oxidoreductase system. Short-chain ubiquinone analogues as potent stimulators. J. Bioenerg. Biomembr 28, 531-.[Medline]

Valls, V., Castelluccio, C., Fato, R., Genova, M. L., Bovina, C., Saez, G., Marchetti, M., Parenti Castelli, G. and Lenaz, G (1994). Protective effect of exogenous Coenzyme Q against damage by adriamycin in perfused rat liver. Biochem. Mol. Biol. Int 33, 633-.[Medline]

Villalba, J. M., Navarro, F., Cordoba, F., Serrano, A., Arroyo, A., Crane, F. L. and Navas, P (1995). Coenzyme Q reductase from liver plasma membrane: purification and role in trans-plasma-membrane electron transport. Proc. Natl. Acad. Sci. USA 92, 4887-.[Abstract/Free Full Text]

Villalba, J. M., Navarro, F., Gomez-Diaz, C., Arroyo, A., Bello, R. I. and Navas, P (1997). Role of cytochrome b5 reductase on the antioxidant function of Coenzyme Q in the plasma membrane. Molec. Aspects Med 18, 7-.

Yakes, F. M. and Van Houten, B (1997). Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc. Natl. Acad. Sci. USA 94, 514-.[Abstract/Free Full Text]

Yoneda, M., Katsumata, K., Hayakawa, M., Tanaka, M. and Ozawa, T (1995). Oxygen stress induces an apoptotic cell death associated with fragmentation of mitochondrial genome. Biochem. Biophys. Res. Commun 209, 723-.[Medline]

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