ADRIAN, R. H. (1969). Rectification in muscle. Prog. Biophys. molec. Biol. 19, 341Ð369.
BERTL, A. AND SLAYMAN, C. L. (1990). Cation-selective channels in the vacuolar membrane of
Saccharomyces: Dependence on calcium, redox state and voltage. Proc. natn. Acad. Sci. U.S.A. 87,
7824Ð7828.
BISSON, L. F. AND FRAENKEL, D. G. (1982). Involvement of kinases in glucose and fructose uptake by
Saccharomyces cerevisae. Proc. natn. Acad. Sci.U.S.A. 80, 1730Ð1734.
BLATT, M. R. AND SLAYMAN, C. L. (1983). KCl leakage from microelectrodes and its impact on the
membrane parameters of a nonexcitable cell. J. Membr. Biol. 72, 223Ð234.
CALDWELL, J. H., VANBRUNT, J. AND HAROLD, F. M. (1986). Calcium-dependent anion channel in the
water mold, Blastocladiella emersonii. J. Membr. Biol. 89, 85Ð97.
CIANI, S., KRASNE, S., MIYAZAKI, S. AND HAGIWARA, S. (1978). A model for anomalous rectification:
Electrochemical-potential-dependent gating of membrane channels. J. Membr. Biol. 44, 103Ð134.
CIRILLO, V. P. (1989). Sugar transport in normal and mutant yeast cells. Meth. Enzymol. 174, 617Ð622.
CONWAY, E. J.(1960). Discussion. In Regulation of the Inorganic Ion Content of Cells; Ciba Fndn Study
Gp No. 5 (ed. G. E. W. Wolstenholme and C. M. O'Connor), p. 65. Boston: Little, Brown and Co.
CRAMER, C. L., WAUGHN, L. E. AND DAVIS, R. H. (1980). Basic amino acids and inorganic
polyphosphates in Neurospora crassa: Independent regulation of vacuolar pools. J. Bacteriol. 142,
945Ð952.
EILAM, Y. OTHMAN, M. AND HALACHMI, D. (1990). Transient increase in Ca 2+ influx in Saccharomyces
cerevisiae in response to glucose: effects of intracellular acidification and cAMP levels. J. gen.
Microbiol. 136, 2537Ð2543.
EILAM, Y. AND OTHMAN, M.(1990). Activation of Ca2+ influx by metabolic substrates in Saccharomyces
cerevisiae: role of membrane potential and cellular ATP levels. J. gen. Microbiol. 136, 861Ð866.
FULLER, F. B. AND PICKARD, B. G. (1972). Spontaneous electrical activity in Coprinus.
Z. Pflanzenphysiol. 67, 291Ð292.
GHOSH, A. AND CHANCE, B. (1964). Oscillations of glycolytic intermediates in yeast cells. Biochem.
biophys. Res. Comm. 16, 174Ð181.
GILLIES, R. J. (1982). Intracellular pH and proliferation in yeast, Tetrahymena and sea urchin eggs. In
Intracellular pH: Its Measurement, Regulation and Utilization in Cellular Function (ed. R. Nuccitelli
and D. W. Deamer), pp. 341Ð359. New York: A. R. Liss.
GOMEZ-LAGUNAS, F., PEÑA, A., LIÉVANO, A., AND DARSZON, A. (1989). Incorporation of ionic channels
from yeast plasma membranes into black lipid membranes. Biophys. J. 56, 115Ð119.
GUSTIN, M. C., MARTINAC, B., SAIMI, Y., CULBERTSON, M. R. AND KUNG, C. (1986). Ion channels in
yeast. Science 233, 1195Ð1197.
GUSTIN, M. C., ZHOU, X.-L., MARTINAC, B. AND KUNG, C.(1988). A mechanosensitive ion channel in the
yeast plasma membrane. Science 242, 762Ð765.
Patch-clamp studies on yeast cation channels
HAGIWARA, S. AND TAKAHASHI, K. (1974). The anomalous rectification and cation selectivity of the
membrane of a starfish egg cell. J. Membr. Biol. 18, 61Ð80.
HALACHMI, D. AND EILAM, Y. (1989). Cytosolic and vacuolar Ca2+ concentrations in yeast cells
measured with the Ca2+-sensitive fluorescence dye indo-1. FEBS Lett. 256, 55Ð61.
HAMILL, O. P., MARTY, A., NEHER, E., SAKMANN, B. AND SIGWORTH, F. J.(1981). Improved patch-clamp
techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers
Arch. 391, 85Ð100.
HIRATA, R., OHSUMI, Y., NAKANO, A., KAWASAKI, H., SUZUKI, K. AND ANRAKU, Y. (1990). Molecular
structure of a gene, VMA1, encoding the catalytic subunit of H+-translocating adenosine
triphosphatase from vacuolar membranes of Saccharomyces cerevisiae. J. biol. Chem. 265,
6726Ð6733.
HODGKIN, A. L. AND HOROWICZ, P. (1959). The influence of potassium and chloride ions on the
membrane potentials of single muscle fibers. J. Physiol., Lond. 148, 127Ð160.
IIDA, H., YAGAWA, Y. AND ANRAKU, Y. (1990). Essential role for induced Ca2+ influx followed by
[Ca2+]i rise in maintaining viability of yeast cells late in the mating pheromone response pathway: A
study of [Ca2+]i in single Saccharomyces cerevisiae cells with imaging of fura-2. J. biol. Chem. 265,
13391Ð13399.
LÄUGER, P. AND STARK, G. (1970). Kinetics of carrier-mediated ion transport across lipid bilayer
membranes. Biochim. biophys. Acta 211, 458Ð466.
LICHKO, L. P., OKOROKOV, L. A. AND KULAEV, I. S. (1982). Participation of vacuoles in regulation of
levels of K+, Mg2+ and orthophosphate ions in cytoplasm of the yeast Saccharomyces carlsbergensis.
Archs Microbiol. 132, 289Ð293.
MARTINOIA, E., HECK, U., BOLLER, TH., WIEMKEN, A. AND MATILE, PH. (1979). Some properties of
vacuoles isolated from Neurospora crassa slime variant. Archs Microbiol. 120, 31Ð34.
MILLER, A. J., VOGG, G. AND SANDERS, D. (1990). Cytosolic calcium homeostasis in fungi: Roles of
plasma membrane transport and intracellular sequestration of calcium. Proc. natn. Acad. Sci. U.S.A.
87, 9348Ð9352.
MÜLLER U., MALCHOW, D. AND HARTUNG, K. (1986). Single ion channels in the slime mold
Dictyostelium discoideum. Biochim. biophys. Acta 857, 287Ð290.
NAKAMURA, Y., NAKAJIMA, S. AND GRUNDFEST, H. (1965). Analysis of spike electrogenesis and
depolarizing K inactivation in electroplaques of Electrophorus electricus, L. J. gen. physiol. 49,
321Ð349.
OKOROKOV, I. A., KULAKOVSKAYA, T. V., LICHKO, L. P. AND POLOROTOVA, E. V. (1985). H+/ion antiport
as the principal mechanism of transport systems in the vacuolar membrane of the yeast
Saccharomyces carlsbergensis. FEBS Lett. 192, 303Ð306.
POLAKIS, E. S. AND BARTLEY, W. (1966). Changes in the intracellular concentrations of adenosine
phosphates and nicotinamide nucleotides during aerobic growth cycle of yeast on different carbon
sources. Biochem. J. 99, 521Ð533.
RICHARD, E. A. AND MILLER, C. (1990). Steady-state coupling of ion-channel conformations to a
transmembrane ion gradient. Science 247, 1208Ð1210.
SERRANO, R.(1977). Energy requirements for maltose transport in yeast. Eur. J. Biochem. 80, 97Ð102.
SLAYMAN, C. L. (1992). Channels, pumps and osmotic machines in plants: A tribute to W. J. V.
Osterhout. In The Biological Century (ed. R. Barlow, G. Weissmann and J. Dowling). Cambridge,
MA: Harvard University Press. (in press).
SLAYMAN, C. L., L ONG, W. S. AND GRADMANN, D. (1976). 'Action potentials' in Neurospora crassa, a
mycelial fungus. Biochim. biophys. Acta 426, 732Ð744.
UCHIDA, E., OHSUMI, Y. AND ANRAKU, Y.(1988). Characterization and function of catalytic subunit a of
H+-translocating adenosine triphosphatase from vacuolar membranes of Saccharomyces cerevisiae. A
study with 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole. J. biol. Chem. 263, 45Ð51.
WADA, Y., OHSUMI, Y., TANIFUJI, M., KASAI, M. AND ANRAKU, Y. (1987). Vacuolar ion channel of the
yeast, Saccharomyces cerevisiae. J. biol. Chem. 262, 17260Ð17263.
WIEMKEN, A. AND DÜRR, M. (1974). Characterization of amino acid pools in the vacuolar compartment
of Saccharomyces cerevisiae. Archs. Microbiol. 101, 45Ð57.
WIEMKEN, A., SCHELLENBERG, M. AND URECH, K.(1979). Vacuoles: The sole compartments of digestive
enzymes in yeast (Saccharomyces cerevisiae)? Archs. Microbiol. 123, 23Ð35.