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Fig. 5. Simulation of simultaneous changes of membrane potential and intracellular Ca²⁺ concentration ([Ca²⁺]_i) for Case III of the computational model as described in Appendix 1. Membrane potential fluctuations ${delta}$ V(t) and fluctuation ratios of intracellular Ca²⁺ concentration ${delta}$ ${rho}$ _i(t) are defined as ${delta}$ V(t) ${equiv}$ V(t)–<V(t)> and ${delta}$ ${rho}$ _i(t) ${equiv}$ [ ${rho}$ _i(t)–< ${rho}$ _i(t)>]/< ${rho}$ _i(t)>, respectively, where <V(t)> and < ${rho}$ _i(t)> are long time averages of membrane potential V(t) and intracellular Ca²⁺ concentration ${rho}$ _i(t), respectively. Fluctuation ratios of intracellular Ca²⁺ concentration ${delta}$ ${rho}$ _i(t) are indicated as changes in [Ca²⁺]_i in the ordinate.

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