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Fig. 3. (A–E) pHi changes induced by bath application of 10 mmol
l–1 cAMP (A), 10 µmol l–1 8-CPT-cAMP (B),
100 µmol l–1 of the adenylyl cyclase inhibitor forskolin
(C) and 500 µmol l–1 of the phosphodiesterase inhibitor
IBMX (D). These experiments show that increases in intracellular cAMP
concentration mimic the acidifying effect of 5-HT stimuli. (E) Quantitative
analysis of the experiments. Data are means ± s.e.m.; the number of
experiments is given in parentheses.