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Figure 2


Fig. 2. Linear RGD-peptides reduce the percentage of spreading endoneurial phagocytes in vitro. (Ai and Aii) Photographs of non-spreading (i) and spreading (ii) endoneurial phagocytes cultured in ABS. (B) Percentage of endoneurial phagocytes showing a spreading response after culturing in the presence of uncoated monodispersed polystyrene carboxylated Fluoresbrite YG microspheres in ABS only, ABS + 100 µmol l–1 SDGRG and ABS + 100 µmol l–1 GRGDS. The addition of GRGDS significantly reduced the percentage of spreading cells. (C) Percentage of endoneurial phagocytes showing a spreading response after culturing in the presence of fibronectin-coated microspheres in ABS only, ABS + 100 µmol l–1 SDGRG and ABS + 100 µmol l–1 GRGDS. Again, the addition of GRGDS significantly reduced the percentage of spreading cells. Scale bar in A, 10 µm. ***P<0.001.





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