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Figure 4


Fig. 4. (A) Stretch of single rat (top) and single trout (bottom) ventricular myocytes held between carbon fibres with resting and stretched sarcomere length (SL) shown on the image. Scale bars, 10 µm. (B) Mean SL– active tension relationships for trout (blue) and mammalian (red) ventricular myocytes where 1.0=1.84±0.02 µm for x-axis and 1.0=0.19±0.03 nN µm–2 for y-axis. The red square (ferret) and red triangle (rat) are data extrapolated to the peak of the mammalian length–tension relationship (2.2 µm). Boxes show the operating range of SLs over which each species act and the corresponding changes in force [adapted from Shiels et al. (Shiels et al., 2006)]. Mammalian data (rat and ferret) are replotted from Cazorla et al. (Cazorla et al., 2000a).





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