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Figure 6


Fig. 6. Age-related changes of GAD67 message and protein levels in A1 and parietal cortex (PtA) of middle-aged and aged FBN rats compared to young adult rats. (A) Significant age-related changes in GAD67 message levels were seen across all layers of A1 in middle-aged and aged FBN rats (except layer IV of middle-aged A1). Significant GAD67 message decreases within PtA occurred only in the aged group. (B) Whereas all layers of middle-aged and aged A1 showed significant age-related decreases in GAD67 protein, in PtA GAD67 protein levels showed no age-related decreases except in layer IV of middle-aged and aged, and in middle-aged layer VI (*P<0.05). (Modified from Ling et al., 2005.)





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