spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 3


Fig. 3. Conditioned place preference persists over a 3-week period of abstinence from nicotine or ethanol. (A) Following 4 weeks of daily 20 min exposure to 30 µmol l–1 nicotine (black bars) fish showed a significantly greater change in place preference for the treatment side compared with control water-treated fish (grey bars; paired t-test *P<0.05). The change in preference exhibited by nicotine-treated fish was significantly greater than the change in preference exhibited by control, water-treated fish 24 h, 7 or 21 days after last drug exposure (two-sample t-test, P<0.05): control, water-treated fish showed no significant change in preference. The place preference for the treatment side after 21 days of abstinence was significantly less than the preference after 24 h of abstinence (two-sample t-test, **P<0.05). (B) 4 weeks of daily 20 min exposure to 175 mmol l–1 ethanol (black bars) induced a significant change in preference compared with control, water treatment (grey bars; *P<0.05, two-sample t-test). This preference persisted over 3 weeks of abstinence.





Right arrow Return to article