|
| |
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 2. Transcriptome discovery does not reach a plateau. (A–D) Rate of gene
discovery as a function of the accumulated number of sequences. Gene discovery
is represented from the number of 3' end clusters identified. A and B
refer to a mixed cell line library; C and D to an embryo pituitary subtracted
library (Carninci et al.,
2003). (A,C) Internal redundancy in terms of novelty of 3'
ESTs (y axis) compared to the sequenced cDNAs (x axis)
within the library. (B,D) Novelty rate of these two libraries versus
the entire RIKEN database of 1.4 million 3' ESTs (axes as in A and B).
Note that the discovery rate, although different, is far from reaching a
plateau, suggesting the existence of a much larger number of yet undetected
RNAs in each tissue/cell line. The pituitary gland library was prepared at the
end of the project, and so far has identified more than 2000 new
transcripts.
|
