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Figure 4


Fig. 4. Modulation of taste sensitivity of gustatory neurons to sugar after starvation. The response of the gustatory neurons sensitive to sugar is estimated by the number of spikes during the first second after stimulation with 100 mmol l–1 glucose. Results are normalized on response prior to starvation for each genotype. After starvation, the activity of neurons sensitive to sugars is increased by approximately 20% in wild type, whereas it remains unchanged for to1 (takeout mutant), suggesting that to1 gustatory neurons do not modulate their activity after a starvation period. This phenotype is rescued by directed genetic expression of to within the to-producing cells. The number in each box represents the number of sensilla recorded for each genotype. CS, Canton Special; rescue, tim-GAL4/UAS-to in a to1 genetic background. Data presented are recorded from males. *P<0.05; **P<0.001. Mean ± s.e.m.





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