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Fig. 7. Serotonin increases resting muscle tension most strongly at the coldest
temperatures. (A) Bath temperature recorded as a function of time illustrating
the change from 2°C to 22°C and back to 2°C before and during
application of 50 nmol l1 5-HT (hatched bar). (B) Resting
muscle tension in the same preparation recorded at temperatures indicated in
A. (C) Muscle tension (mean ± s.e.m.) recorded at 2°C and 22°C
in the absence and presence (hatched bar) of 5-HT (50 nmol
l1) in the same seven preparations. Values for P
(paired t-test) are indicated by horizontal brackets. The break in
the x-axis indicates the distinction between the first temperature
warming protocol and the second.