|
| |
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 6. Modulation of neurally evoked contractions by 5-HT is temperature
dependent. (A) Neurally evoked contractions recorded under control conditions
(lower traces) and in the presence of 50 nmol l–1 5-HT (upper
traces) at the indicated temperatures. Each trace is the average of ten
consecutive recordings. (B) Temperature dependence of neurally evoked
contraction strength in muscle fibers (N=6) in the absence (open
symbols) and presence (closed symbols) of 5-HT (50 nmol l–1).
Control data are normalized relative to the average contraction amplitude
recorded at 2°C (error bars are not larger than the symbols); 5-HT data
are normalized relative to the potentiating effect of 5-HT on contraction
amplitude (an increase of 1112%) at 2°C in the same preparations. (C)
Potentiation of neurally evoked contractions by 50 nmol l–1
5-HT recorded at bath temperatures between 2°C and 22°C (N=5
muscle fibers at 20°C and 22°C, N=6 at all other
temperatures). Symbols illustrate the logarithm of the ratio of neurally
evoked contraction strength after application of 5-HT with respect to the
control value at the same temperature. Asterisks indicate values that are
significantly different from data recorded at 2°C (independent
t-test, P<0.05).
|
