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Figure 3


Fig. 3. Inhibition of PDF-degrading activity of D. melanogaster head membranes by phosphoramidon and thiorphan. Inhibition curves for phosphoramidon (filled triangles, IC50=0.15 µmol l–1) and thiorphan (open squares, IC50=1.2 µmol l–1) were generated by measuring the formation of PDF8-18 from PDF in the presence of different concentrations of inhibitors, as described in Materials and methods. Data are expressed relative to uninhibited activity and IC50 values were calculated using FigP (Biosoft).





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