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Fig. 3. Dynamic clamp studies showing non-monotonic firing response. (A,B) Example
traces from one ELL pyramidal neuron showing membrane potential (black,
Vm) and injected current (gray, Im)
for two different values of re (5 Hz and 20 Hz). Scale
bars are the same for both A and B (40 mV, 0.4 nA, 1 s). (C) Non-monotonic
firing response of ELL pyramidal neurons; normalized mean firing rate (mean
± s.d.; 16 neurons) is shown as a function of mean excitation rate,
re (binned in 2 Hz increments).