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Fig. 10. Summary figure of polarized radiographs focused on the spine from one
cohort (CC1) of experimental animals. (A) Paired female CC1-633; (B) paired
male CC1-893; (C) colony control CC1-3581. In each panel, the first radiograph
was taken during the baseline period; the second radiograph was taken at the
end of the study (45 weeks after removal from reproductive suppression). The
horizontal line in the center of each radiograph is aligned with the top of
the vertebral body of L1. The diagram illustrates contrasts in lumbar
lengthening from the beginning to the end of the study across experimental
groups. The number on the center of the horizontal line indicates the percent
of length gained in the lumbar spine by that animal over the duration of the
50-week study. The radiopaque cylindrical objects seen near the cervical spine
are identification microchip implants.