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Figure 8


Fig. 8. Alignment of seven protein sequences (created by ClustalW; http://www.ebi.ac.uk/Tools/clustalw/index.html/) from the first subgroup of the phosducin family (Blaauw et al., 2003). In Blepharisma, serine residues of Pdc – the potential phosphorylation sites – are marked red, and residues highlighted in green form the characteristic amino acid motif (RSXSXP) that is believed to be involved in 14-3-3 protein binding to Pdc. Residues of human Pdc that contact Gβ are denoted by (+) above the aligned sequences. Protein accession numbers: Blepharisma japonicum Pdc, gi_124020703; Dictyostelium discoideum PhLP1, gi_33331889; Homo sapiens Pdc, gi_2967590; Homo sapiens PhLP1, gi_5430700; Danio rerio Pdc1, gi_38174547; Rattus norvegicus PhLP1, gi_66911418; Cryptonema parasitica Pdc, gi_6714949.





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