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Fig. 6. Physical basis for diffusion spectrum imaging (DSI). DSI is a high
resolution diffusion-weighted imaging technique which determines the complete
spin displacement function by acquiring a large number of images with varying
diffusion weighting and angularity. This results in the generation of a
probability density function (PDF) for the entire set of possible molecular
displacements, and thus depicts the set of principal fiber orientations based
on the properties of the diffusion maxima. (A) Two sets of model fibers drawn
with arbitrary angular separation. (B) In order to simplify the visualization
of 3-D diffusion, the PDF is converted to an orientational diffusion function
(ODF), which provides a probability distribution for diffusion for a set of
angular directions, weighted by the magnitude of the diffusion.
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