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Fig. 1. Domain architecture of the midgut chitin synthase CHS2. The two black
horizontal lines represent the apical brush border membrane of midgut columnar
cells. Horizontal bars represent intra- or extracellular domains and vertical
bars transmembrane helices. (A) Aminoterminal transmembrane region; (B)
cytoplasmic catalytic domain; (C) carboxyterminal transmembrane region; the
numbers refer to single domains within each region. Those domains that were
tested as baits in the yeast two-hybrid system are coloured dark grey. UDP,
uridine 5'-diphosphate; GlcNAc, N-acetyl-D-glucosamine.