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Fig. 5. (A,B) Breathing frequency (breaths min-1), (C,D) integrated
breath area (Vxs) and (E,F) total ventilation index (Vxs
min-1) as a function of the inspired CO2 level recorded
in vivo from control (A,C,E) and CHC (B,D,F) toads. Open circles
(A,C,E) and open squares (B,D,F) represent animals with the olfactory nerves
intact (OI). Filled circles (A,C,E) and filled squares (B,D,F) represent
animals that underwent olfactory denervation (OD) prior to the 10-day period
of CHC (or control conditions). The data are plotted as the mean ± 1
s.e.m. Letters (a-c) represent significant differences at the different
inspired CO2 levels within any group. A number sign (#) represents
a difference between the OI and OD groups. A plus sign (+) represents a
difference between the control and CHC groups (comparing panel A with B, C
with D and E with F).