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Fig. 4. The effects of chronic hypercapnia (CHC; open squares), chronic hyperoxia
(CHO; filled circles) and chronic hyperoxic hypercapnia (CHH; filled
triangles) on (A) fictive breathing frequency (fictive breaths
min-1), (B) fictive episodes min-1, (C) fictive breaths
per episode, (D) integrated fictive breath area (Vxs), (E) total fictive
ventilation index (Vxs min-1) and (F) fictive breath duration
(s) recorded from in vitro brainstem-spinal cord preparations. The
data are plotted as the mean ± 1 s.e.m. Letters (a-c) represent
significant differences at the different artificial cerebral spinal fluid
(aCSF) pH levels within any group. A plus sign (+) represents a difference
from the CHC value. A number sign (#) represents a difference from the CHH
value.