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Fig. 3. (A) Stage-dependent changes in fictive lung burst frequency during
noradrenaline (NA; 5 µmol l–1) application. The histograms
(left) show the mean data and the trigeminal neurograms (
V, trigeminal
nerve; right) show representative recordings obtained under baseline
conditions and following NA bath application. Data are reported for both stage
groups (pre-metamorphic: grey bars, N=6; and adults: black bars,
N=6). (B,C) The same experiment was performed in the presence of the
GABAA/glycine antagonist mixture (bicuculline 1.25 µmol
l–1/strychnine 1.5 µmol l–1) in both
stage groups. For these experiments, representative trigeminal neurograms
showing respiratory-related activity observed under each condition are shown
below the histograms. Values are means ± s.e.m. *Values
statistically different from baseline at P<0.05;
value statistically different from corresponding mixture
value at P<0.05.