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Figure 7


Fig. 7. Excitatory actions of cholinergic agonists on the isolated cardiac ganglion (CG). (A) Extracellular recording from the trunk in control (top trace) and during 10–5 mol l–1 pilocarpine perfusion (bottom trace). (B) Pilocarpine (Pilocarp.) significantly increased the burst frequency, duty cycle, number of spikes per burst and spike frequency in the burst (Student's t-test; N=8; *P<0.05; **P<0.01). (C) Same preparation shown in A during wash (top trace) and in the presence of 10–5 mol l–1 nicotine (bottom trace). (D) Nicotine significantly increased the duty cycle, number of spikes per burst and spike frequency in the burst (Student's t-test; N=8; *P<0.05; **P<0.01).





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