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Fig. 10. Bicuculline-insensitive inhibition induced by parallel fibers (PF)
stimulation. (A,B) Superimposed traces of the responses to paired pulse
stimulation of the PF. The controlled paired stimuli in A were delivered at
30, 40, 60 and 80 ms intervals. The paired stimuli in the presence of
bicuculline (100 µmol l–1) (B) were delivered at 30, 50,
70, 90 and 110 ms intervals. Each record is an average response to eight
consecutive stimuli delivered at a rate of 0.1 Hz. (C) The amplitude of the
responses to the second stimulus, normalized by the amplitude of the first
response, as a function of the inter-stimuli interval. Diamonds indicate
responses before, and squares, responses after addition of bicuculline.
N=9 (control), N=3 (+bicuculline). (D) The responses
to a pair of stimuli delivered to the PF at an interval of 30 ms. Each trace
shows the response to different stimulus intensity, increasing from top to
bottom. (E) The amplitude (right axis) of the response to the first (circles)
and second (squares) stimulus as a function of stimulus intensity. Triangles
indicate the relative amplitude of the second response (left axis) as a
function of stimulus intensity.
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