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Fig. 4. Hoa-SK I and Hoa-SK II evoked increases in the frequency and amplitude of
heart contractions. Both frequency and amplitude of cardiac contractions in
the isolated heart increased by approximately 15% when the hearts were
perfused with Hoa-SK I; frequency increased on average by 20% and amplitude by
25% when the hearts were perfused with Hoa-SK II. All changes were
significantly different from 0 (two-tailed t-tests):
*P<0.05; **P<0.01; N=11
preparations for Hoa-SK I, N=14 preparations for Hoa-SK II. Values
are means ± s.e.m.