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Fig. 4. Phylogenetic analysis of cytoplasmic lamprey carbonic anhydrase and other
cytoplasmic
-carbonic anhydrase isozymes. The phylogenetic tree was
constructed using neighbour joining analysis with support for nodes assessed
using bootstrap analysis. The tree was ordered using human carbonic anhydrase
Va and Vb as a monophyletic outgroup. Branches are drawn to scale (bar) with
the length of 0.1 approximating replacement of 10% of the amino acids in the
protein alignment (no Poisson correction for multiple hits).