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Figure 9


Fig. 9. Cardiac performance in isolated hearts (N=4) in vitro as a function of temperature. (A) Examples of blood flow in sternal artery measured at the indicated temperatures. (B) Heart rate (mean ± s.d.) measured as a function of temperature. (C) Stroke volume (mean ± s.d.) measured as a function of temperature. The data show a linear trend with an estimated slope of –0.070 (s.e.m.=0.017, P<0.001). (D) Cardiac output (mean ± s.d.), measured as a function of temperature, is represented by the symbols and solid lines. The broken line represents the estimated means based on the quadratic equation as follows: mean cardiac output=19.18(±5.4)+5.01(±0.91)x (temperature)–0.25(±0.04)x(temperature)2, where values in parentheses are standard errors. The estimated maximum for the fitted curve is at temperature=9.90, 95% confidence interval (3.6, 16.2). *Data are significantly different from values at 2°C (P<0.05).





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