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Figure 2


Fig. 2. Changes in pHi in isolated toad myocytes subjected to hypercapnic acidosis in the absence or presence of Na+/H+ exchanger (NHE) inhibition. (A) In the the absence of cariporide, the initial fall in pHi was followed by restitution towards the 5% CO2 values, in spite of the persistent extracellular acidosis. No pHi recovery was observed in the presence of cariporide (5 µmol l–1). (B) Overall results of five experiments of this type. *P<0.05 with respect to values with cariporide.





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