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Figure 5


Fig. 5. The proctolin-induced potentiation of K+-induced contracture is prevented by the PKC inhibitor BIM-1 and mimicked by the PKC activator PMA. Summary of independent experiments showing the maximum amplitude of contractures normalised to controls: in the presence of 1 µmol l-1 proctolin (N=8), in the presence of proctolin and 10 nmol l-1 BIM-1 (N=5), in the presence of BIM-1 (N=4) and in the presence of 1 µmol l-1 of the PKC activator PMA (N=7) during high K+-saline application for 5 min. *Significantly different from controls, P<0.05.





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