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Fig. 2. (A) Alignment of protein sequences for class I GLUTs from Atlantic cod. The
single letter code is used for the amino acids. Gaps in the amino acid
sequences are indicated with a dash (-). Positions where there is a single,
fully conserved residue are indicated with an asterisk (*),
positions with a `strong' group fully conserved are indicated with a colon
(:), and positions with a `weaker' group fully conserved are indicated with a
dot (.). Numbered lines above the sequences indicate the approximate positions
of the predicted membrane spanning helices. Residues that are highly conserved
in all glucose transporters are highlighted in grey, and those that are
specific to class I glucose transporters are highlighted in black. Residues
discussed with respect to GLUT4 are indicated by a grey box and those to GLUT2
with a white box. (B) Alignment of GPDH protein sequences from Atlantic cod
and other fish species.