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Fig. 6. Test for savings of extinction memory during reinstatement in control and
cocaine-exposed snails. After operant conditioning, animals were exposed to
extinction training but no pneumostome stimulus was administered (shown by
ovals E1, 2 and 3; no data indicated). Testing for extinction memory was
conducted during the Test for Savings 2 h after the last extinction training
session, and this Test for Savings session is shown for the same animals as
those used for the data in Fig.
5. (A) Control and (B) 0.1 µmol l-1 cocaine treated.
Values are mean ± s.e.m. for number of pneumostome openings. Animals
treated with 0.1 µmol l-1 cocaine did not meet the requirements
for extinction memory during reinstatement. Snails pretreated with 0.1 µmol
l-1 cocaine showed a significant reduction in the number
of pneumostome openings on the Test for Savings compared with the Memory Test.
Training session 1; 2, Training session 2; MT, Memory Test;
TS*P<0.05 compared with MT within the same treatment
group.
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