spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 2


Fig. 2. H2S has two dose-dependent effects on pre-contracted (10–7 mol l–1 U-46619) bovine pulmonary arteries. H2S appears to produce a dose-dependent relaxation between 10–8 and 10–5 mol l–1, whereas above 10–5 mol l–1 it produces a dose-dependent constriction. The EC50 for relaxation (5.5±1.8x10–7 mol l–1) is significantly (P≤0.05) different from the EC50 for contraction (3.7±1.5x10–4 mol l–1). (A) Single trace of cumulative doses; arrowheads indicate log[H2S] (in mol l–1) and time of addition of U-46619; W=wash. (B) Relaxation (filled circles); contraction (open squares; values extrapolated where curves overlap ~10–5 mol l–1). Values are means ± s.e.m. of 8 vessels. Stippled rectangle indicates range of H2S reported in the rat plasma (see text for details).





Right arrow Return to article