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Figure 6


Fig. 6. The effect of increasing the rate of mitochondrial ATP production and myosin ATPase activity during steady-state contraction in small fibers on the temporal and spatial profiles of AP (A,C,E) and ATP (B,D,F). Metabolite concentrations during a typical steady-state contraction, where Vm,mito=1.00x10-14 mmol µm-2 s-1 and Vm,myo=1 mmol l-1 s-1 (A,B), during steady-state with a threefold increase in Vm,mito and Vm,myo (C,D), and during steady-state with a sevenfold increase in Vm,mito and Vm,myo (E,F).





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