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Fig. 4. Profile of agNAT8-mediated amino acid-induced currents. The upper line
combines typical currents of agNAT8-expressing oocytes upon a trial
application of selected substrates at 2 mmol l-1 concentrations.
The lower histogram incorporates mean values of induced responses upon
application of 1 mmol l-1 concentration of selected substrates
normalized to Phe induced currents (values are mean + s.d.; N
3
recordings for at least three different oocytes for each data point). Holding
potentials for all recordings were -50 mV. Standard abbreviations of amino
acids and neurotransmitters are used. Arrows highlight the D-isomer
of phenylalanine.