spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 2


Fig. 2. Alignment and reconstruction of agNAT8 structure. (A) Sequence/structure alignment of characterized insect transporters relative to the first crystallized bacterial NAT from A. aeolicus, LeuTAa (Yamashita et al., 2005). (B) 2D structure of agNAT8 based on structural homology with the LeuTAa protein sequence. NCBI Accession no.: LeuTAa, NP_214423 (PDB no., 2A65); msKAAT1, AAC24190; msCAATCH1, AAF18560; aeAAT1, AAR08269; agNAT8, AAN40409. Filled and open stars represent putative cationic gates at extra- and intracellular interfaces, respectively. Squares indicate putative substrate binding sites; red and blue spheres outline sites, which interact with the first and second sodium ion respectively. Red and yellow boxes show putative glycosylation motifs and disulfide bridges, respectively. The 12 transmembrane domains are numbered 1-12.





Right arrow Return to article