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Figure 4


Fig. 4. The change in maximum cardiac output (A) and maximum cardiac power output (B) of perfused rainbow trout hearts at 10°C under hypoxic, hyperkalemic (5 mmol l–1), acidotic (pH 7.5) perfusate with both tonic (5 nmol l–1) and maximal (500 nmol l–1) adrenergic stimulation. Individual groups of hearts were exposed to specific hypoxia levels as indicated on the x-axis, and results are shown from several series of experiments, each indicated as a separate line segment. The series were as follows. Series III: 12.6 kPa (N=6), 10 kPa (N=10), 6.7 kPa (N=6), series IV: 5.0 kPa (N=7), 3.3 kPa (N=8), 2.7 kPa (N=5), and series V: 2.7 kPa (N=6), 2.0 kPa (N=6) and 1.3 kPa (N=4). Values are reported as percent change from an original assessment under normoxic conditions. One-way repeated-measures ANOVA and Holm–Sidak multiple comparisons tests were used to compare treatment means and each heart acted as its own control. Values shown are means ± s.e.m. *Significant difference from normoxia (P=0.05).





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